Txo cov mob qog noj ntshav Probiotics

Txo cov mob qog noj ntshav Probiotics

Specifications: 0.5 g × 60 capsules/box Formula (cov ntsiab lus rau ib ntsiav tshuaj): Lactobacillus johnsonii LBJ456®: 12 Billion CFU Lactobacillus acidophilus HH-LA26: 8 Billion CFU Bifidobacterium lactis HH-BA68, CFU: acerola, mulberry txiv hmab txiv ntoo hmoov, galactooligosaccharides, ...

Khoom Taw qhia

 

Specifications: 0.5 g × 60 capsules/box
Formula (cov ntsiab lus ntawm ib ntsiav tshuaj):
Lactobacillus johnsonii LBJ456®: 12 Billion CFU
Lactobacillus acidophilus HH-LA26: 8 Billion CFU
Bifidobacterium lactis HH-BA68: 10 Billion CFU
Cranberry, acerola, mulberry txiv hmab txiv ntoo hmoov, galactooligosaccharides, inulin
Cov mis probiotic no yog ib hom tshuaj probiotic kho tau los tiv thaiv qog noj ntshav. Cov mis probiotic no muaj patented thiab scientifically proven probiotic hom Lactobacillus johnsonii LBJ456®, uas yog scientific proven rau:
√ Muaj zog adhesion thiab colonization muaj peev xwm
√ Cov nyhuv anti-inflammatory zoo heev
Cov koob tshuaj pom zoo: Noj ib ntsiav tshuaj ib hnub rau tsawg kawg ob lub lis piam.
Cancer yog ib lo lus dav dav rau cov chav kawm loj ntawm cov qog nqaij hlav malignant
Cov kab mob qog noj ntshav yog tus yam ntxwv los ntawm kev txwv tsis pub muaj kev loj hlob thiab tsis muaj qhov kawg, uas noj ntau cov as-ham hauv tus neeg mob lub cev;
Cov qog nqaij hlav cancer tso tawm ntau yam co toxins, ua rau muaj cov tsos mob tshwm sim hauv tib neeg lub cev;
Cov qog nqaij hlav cancer kuj tseem tuaj yeem nthuav tawm, loj hlob, thiab sib npaug thoob plaws hauv lub cev.

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mob cancer cell metastasis
Raws li qee qhov xwm txheej, cov qog nqaij hlav cancer yuav tawm ntawm qhov tseem ceeb, kis mus rau lwm qhov ntawm lub cev los ntawm cov ntshav lossis lymphatic system, thiab tsim cov qog tshiab hauv lwm qhov ntawm lub cev. Cov txheej txheem no hu ua metastasis; metastasis ntawm cov qog nqaij hlav cancer ua rau poob phaus thiab tsis muaj zog hauv lub cev. , anemia, poob qab los noj mov, ua npaws, ua rau lub cev ua haujlwm hnyav, thiab lwm yam.

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Cov xwm txheej tam sim no thiab cov xwm txheej ntawm mob qog noj ntshav hauv Tebchaws Meskas[1]
Nws kwv yees tias 609,820 tus neeg yuav tuag los ntawm mob qog noj ntshav hauv Tebchaws Meskas xyoo 2023, uas yog sib npaug rau 1,670 tus neeg tuag txhua hnub.
Ntawm cov txiv neej, feem ntau ua rau tuag yog mob ntsws, prostate, thiab mob qog noj ntshav;
Ntawm cov poj niam, cov neeg tuag coob tshaj plaws yog los ntawm lub ntsws, lub mis, thiab mob qog noj ntshav.

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Duab: kwv yees tus naj npawb ntawm cov neeg tuag thiab hom mob qog noj ntshav loj los ntawm poj niam txiv neej hauv Tebchaws Meskas xyoo 2023

Mob plab thiab mob qog noj ntshav
Cov kab mob 10 trillion nyob rau hauv cov hnyuv tsim ib lub koom haum tshuaj me me, uas cov kab mob phem yuav decompose digested zaub mov thiab lwm yam khoom nyob rau hauv lub cev mus rau ntau yam carcinogens, feem ntau yog nitrosamines, indoles, phenols, theem nrab bile acid.

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Probiotic anti-tumor hom kev ua
① Degrade los yog adsorb carcinogens, yog li txo lawv cov toxicity;
② Txhawb tib neeg lub cev tiv thaiv kab mob thiab tiv thaiv kev loj hlob ntawm cov qog nqaij hlav cancer; inhibit qhov kev loj hlob ntawm cov kab mob putrefactive hauv cov hnyuv los ntawm kev txhim kho cov hnyuv ib puag ncig, yog li tiv thaiv kev tsim cov carcinogens hauv cov hnyuv;
③ Tsim cov tebchaw uas inhibit qhov kev loj hlob ntawm cov qog hlwb lossis cov metabolites uas tua cov kab mob phem.
Anti-tumor mechanism ntawm probiotics [2]
Probiotics muaj peev xwm hloov kho cov kab mob qog noj ntshav,
Probiotics tuaj yeem dhau
(a) Inducing apoptosis,
(b) inhibit mutagenic kev ua,
(c) Downregulate oncogene qhia,
(d) Inducing autophagy,
(e) inhibit kinases,
(f) Reactivation ntawm qog suppressors,
(g) Hloov kho mob qog noj ntshav los ntawm kev tiv thaiv metastasis.

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Daim duab: Schematic daim duab ntawm lub tswv yim ntawm kev siv probiotics los tiv thaiv lossis kho mob qog noj ntshav.


Lactobacillus johnsonii LBJ456®
Source of strain: noj qab nyob zoo nas plab hnyuv
Tus lej sau: CCTCC No: M20191013
Patent luam tawm tus lej: CN111534467A
US Patent Number: US 10,028,983 B2
Gastric acid kam rau ua [3]
Gastric acid kam rau ua yog cov cuab yeej tseem ceeb tshaj plaws ntawm probiotics vim nws txiav txim siab lawv lub peev xwm kom muaj sia nyob hauv txoj hnyuv me thiab yog li siv lawv lub luag haujlwm ua probiotics. Thaum pH thaum kawg mus txog 1.2, txawm hais tias tus naj npawb ntawm Lactobacillus johnsonii poob los ntawm 3 qhov kev txiav txim ntawm qhov loj, nws tsuas yog muaj txoj sia nyob hauv qhov kev sim. Yog li ntawd, tsis tshua muaj zog gastric acid kam rau ua yog ib qho tseem ceeb hauv paus rau nws txoj kev vam meej adherent colonization.

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adhesion
Kev muaj peev xwm ua raws li tus tswv tsev yog qhov tseem ceeb rau kev tshuaj xyuas cov muaj peev xwm probiotics. Nws tau xav tias yuav cuam tshuam nrog kev colonization, kev tiv thaiv kab mob, kev tiv thaiv kev tiv thaiv kab mob, thiab kev txhim kho ntawm kev ua haujlwm tsis zoo. Hauv kev sim hauv vitro monolayer cell adhesion siv LS174T hlwb, cov nyhuv adhesion ntawm Lactobacillus johnsonii LBJ456 yog siab dua li Lactobacillus acidophilus, Lactobacillus plantarum 299V thiab Bifidobacterium lactis HN019.

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Anti-cancer muaj nuj nqi pov thawj
Cov kws tshawb fawb tau rov qab soj ntsuam 118 tus neeg mob uas mob ntsws cancer siab heev uas tau txais kev tiv thaiv kab mob thiab tshuaj xyuas cov quav los ntawm 80 tus neeg mob ntsws cancer. Ntawm 118 tus neeg mob suav nrog, 72 yog cov neeg siv PPI (35% ntawm cov neeg siv probiotics) thiab 46 tsis yog cov neeg siv PPIs (30% ntawm cov neeg siv probiotics).
a) PIB group

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b) PPI + pab pawg tswj hwm probiotic

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c) PPI + tshuaj tua kab mob + probiotics tswj pawg

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Los ntawm kev txheeb xyuas statistical, nws tau pom tias:
a) Kev ciaj sia tag nrho ntawm cov neeg mob uas siv PPIs tau luv luv. Kev tshuaj xyuas pom tias qhov tsis zoo ntawm PPIs no pom tseeb dua hauv cov neeg mob uas tsis siv cov tshuaj probiotics thiab siv tshuaj tua kab mob.
b) Ntawm cov neeg mob uas siv PPIs, qhov kev vam meej tsis muaj sia nyob (PFS) ntawm cov neeg mob siv probiotics tau ntev heev, nrog rau qhov nruab nrab PFS ntawm 250 hnub vs. 88 hnub.
c) Ntawm cov neeg mob siv PPI + tshuaj tua kab mob, qhov kev vam meej tsis muaj sia nyob (PFS) ntawm cov neeg mob siv probiotics kuj tseem ntev dua li cov neeg mob uas tsis siv probiotics.
Nws tuaj yeem pom tau tias qhov cuam tshuam tsis zoo ntawm ob qhov kev siv tshuaj tiv thaiv kab mob tsis zoo (PPI thiab tshuaj tua kab mob) ntawm qhov ua tau zoo ntawm ICB tuaj yeem txo qis los ntawm kev siv cov tshuaj probiotics ua ke.
Lus Cim:
PPI: Ib qho kev tiv thaiv kab mob hauv plab, PPI tuaj yeem ua rau cov kab mob hauv lub qhov ncauj hloov mus rau txoj hnyuv, yog li cuam tshuam tsis zoo rau kev siv tshuaj tiv thaiv kab mob hauv cov neeg mob qog noj ntshav.
PFS: yog hais txog lub sij hawm nruab nrab ntawm kev pib kho thiab kev soj ntsuam ntawm kev kis kab mob lossis kev tuag los ntawm ib qho laj thawj.

Raw khoom los ntawm tib lub hauv paus chiv keeb li tshuaj thiab zaub mov:
Cranberry: Cov physiologically active tshuaj nyob rau hauv cranberries tuaj yeem tiv taus lipid peroxidation ntawm unsaturated fatty acids nyob rau hauv biofilms, tiv thaiv cov qauv thiab kev ua haujlwm ntawm biofilms, thiab tiv thaiv ntau yam kab mob degenerative; Lawv tuaj yeem tiv thaiv kab mob urinary thiab tiv thaiv Helicobacter pylori. , antioxidant, tiv thaiv qog, thiab tiv thaiv kab mob plawv.
Acerola: Acerola txiv hmab txiv ntoo yog ib qho ntawm cov khoom siv ntuj tsim nrog cov ntsiab lus L-ascorbic acid siab tshaj plaws, thiab L-ascorbic acid yog cov khoom siv lom neeg lom zem tshaj plaws ntawm plaub isomers ntawm Vc. L-ascorbic acid koom nrog ntau yam tshuaj lom neeg cov tshuaj lom neeg hauv tib neeg lub cev thiab muaj cov kev siv tshuaj kho mob tseem ceeb hauv kev tswj hwm ntawm tes, ua kom tsis muaj zog, thiab tiv thaiv kab mob.
Mulberry txiv hmab txiv ntoo hmoov: Mulberry polysaccharide yog cov tseem ceeb tshaj plaws bioactive tshuaj nyob rau hauv mulberries, thiab muaj ntau yam physiological kev ua ub no xws li anti-tumor, antioxidant, antibacterial, hypoglycemic, hypolipidemic, thiab kev tiv thaiv kab mob.
Cov ntawv & Patents
[1] 《Cancer statistics, 2023 express
[2] 《 Kev tshawb fawb qhia txog kev noj zaub mov thiab probiotics txhawb kev kho mob melanoma immunotherapy li cas. qhia
[3] 《Probiotic Gastrointestinal Transit and Colonization after Oral Administration: A Long Journey express

 

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