Science thiab Technology Innovation Center Han Qiaoyu Lub Kaum Ob Hlis 29, 2023
Probiotics hais txog cov kab mob muaj sia uas tuaj yeem tsim cov teebmeem uas txhawb kev noj qab haus huv ntawm tus tswv tsev thaum mus txog qee tus lej. Probiotics colonizing cov hnyuv tuaj yeem pab zom cov zaub mov, tsim cov metabolites uas muaj txiaj ntsig zoo rau kev noj qab haus huv ntawm tus tswv tsev, thiab tswj cov homeostasis ntawm lub cev. Probiotics muaj ntau yam teebmeem kev noj qab haus huv, xws li tswj cov hnyuv, tiv thaiv plab hnyuv, antioxidant thiab tswj kev tiv thaiv kab mob, thiab lwm yam, thiab tuaj yeem txo qhov kev pheej hmoo ntawm ntau yam kab mob.
Probiotics tswj cov ntshav qab zib los ntawm kev tswj cov kab mob hauv plab hnyuv, plab hnyuv tiv thaiv kab mob, kab mob hauv plab-hlwb-hlwb axis, kab mob- plab-siab axis, thiab lwm yam. Nws cov txheej txheem ntawm kev ua haujlwm suav nrog: probiotics noj qabzib; txo qis qis-qib o thiab oxidative kev nyuaj siab; tswj cov kab mob hauv plab thiab ua kom luv luv-chain fatty acid cov ntsiab lus; txhim khu kev tiv thaiv; txhim kho insulin tsis kam; probiotics tuaj yeem tsim cov kab mob bacteriocins thiab lwm yam tshuaj, tiv thaiv kab mob pancreatic, txhawb kev ua haujlwm ntawm pancreatic islet, inhibit -glucosidase, thiab lwm yam; cov polypeptides tsim thaum lub sij hawm proliferation ntawm probiotics tuaj yeem ua rau ntawm NOD2 receptors ntawm hypothalamic -aminobutyric acid neurons los ntawm lub hlwb-lub plab axis, inhibiting synapses Cov kev ua ntawm posterior neurons plays lub luag hauj lwm hauv suppressing qab los noj mov thiab txhim kho metabolism.
Ntxiv nrog rau kev tswj cov ntshav qab zib, probiotics tuaj yeem tswj cov ntshav siab los ntawm kev tswj hwm lub cev cov hnyuv thiab txhim kho lub peev xwm antioxidant. Tsis tas li ntawd, probiotics tuaj yeem tiv thaiv kev kub ntxhov los ntawm inhibiting ACE kev ua haujlwm. Txog tam sim no, ntau hom kab mob zoo heev nrog kev tsim tawm siab ntawm ACE inhibitory peptides tau raug tshuaj xyuas, thiab ntau cov txiaj ntsig ntawm tib neeg tau pom tias kev noj cov zaub mov fermented uas muaj ACE inhibitory peptides tuaj yeem pab txo qis ntshav siab.
Probiotics muaj ntau lub tswv yim ntawm kev ua kom txo cov ntshav lipids. Tam sim no, nws ntseeg tau tias muaj plaub lub ntsiab tseem ceeb: nqus cov roj cholesterol los ntawm cov ntshav mus rau hauv cov hlwb los ntawm cov kab mob hauv lub hlwb rau kev siv lossis adsorbing ntawm cov cell membrane thiab tshem tawm ntawm lub cev, yog li txo cov roj cholesterol; tswj cov roj (cholesterol) ntsig txog cov noob qhia theem inhibiting txoj hnyuv nqus ntawm cov cholesterol thiab rog thiab txo cov ntshav lipid; nws txo cov roj cholesterol los ntawm cov khoom xws li cov kua tsib ntsev hydrolase uas tsim los ntawm kev tso tawm hauv lub cev; Nws inhibits cov roj (cholesterol) los ntawm kev siv tshuaj lom neeg xws li cov roj cholesterol ester acyl-CoA inhibitors uas tsim los ntawm kev zais cov enzymes tseem ceeb hauv txoj kev hluavtaws tuaj yeem cuam tshuam kev tsim cov tshuaj precursor, yog li cuam tshuam rau cov qib roj cholesterol.
cov ntaub ntawv:
[1] Li Yongzhen, Zhang Tiantian, Wang Junxian, thiab lwm yam. Lub luag haujlwm ntawm probiotics hauv ntshav qab zib tswj [J/OL]. Daim ntawv tshaj tawm ntawm Microbiology: 1-25 [2023-11-15].
[2] Wang Yuseng. Excavation thiab mechanism kev tshawb fawb ntawm probiotics nrog kev ua haujlwm ntawm kev tiv thaiv kev kub siab [D]. Jiangnan University, 2021.DOI: 10.27169/d.cnki.gwqgu.2021.001027
[3] Sun Qian, Wan Xiangyuan. Kev tshawb nrhiav kev nce qib ntawm probiotics hauv kev txo qis hyperlipidemia thiab hyperglycemia [J]. Phau ntawv Journal ntawm Henan University of Technology (Natural Science Edition), 2018, 39(06): 125-132. DOI: 10.16433/ j.cnki.issn1673-2383.2018.06.022.