Probiotic muaj pes tsawg leeg los txhim kho cov kab mob tsis haum
Patents No.: CN111548961A
Cov muaj pes tsawg leeg ntawm probiotic rau kev txhim kho cov kab mob ua xua yog tus cwj pwm los ntawm cov khoom hauv qab no hauv feem pua ntawm qhov hnyav:
50-95 feem pua ntawm probiotic A thiab 5-50 feem pua ntawm probiotic B;
wherein: cov probiotic A yog lactobacillus johnsonii uas tau khaws cia hauv Suav teb chaw rau hom kab lis kev cai Sau nrog tus naj npawb ntawm CCTCC NO: m20191013.
Cov probiotics B suav nrog ib lossis ntau dua ntawm lactobacillus casei, lactobacillus paracasei, lactobacillus plantarum, lactobacillus rhamnosus thiab lactobacillus reuteri.
Cov kab mob ua xua xws li kab mob ua xua, perennial allergic rhinitis thiab hawb pob yog cov kab mob ua xua ntau tshaj plaws; cov probiotics yog cov kab mob muaj sia nyob muaj peev xwm tiv thaiv thiab txhim kho cov kab mob ua xua, feem ntau yog los ntawm kev txhawb nqa cov receptors ntawm cov kab mob dendritic ntawm cov phab ntsa hauv plab hnyuv thiab khi, ua kom muaj zog thiab ua kom cov protein nyob hauv cov hlwb kom txav mus rau hauv nuclei kom tso tawm ntau cov cytokines, txhim kho cov tsos mob tsis haum los ntawm Txhawb nqa kev nce ntxiv ntawm kev tso tawm ntawm interleukin 12 (IL-12) thiab interferon gamma, thiab inhibiting immunoglobulin IgE los ntawm kev txhawb txoj hnyuv txoj cai Th1 hom tiv thaiv kab mob, yog li txhim kho kev ua xua tshwm sim ntawm Th1 thiab Th2 hom kev tiv thaiv kab mob ntau dhau.
Lub lactobacillus johnsonii tuaj yeem txhawb nqa cov receptors ntawm cov hlwb dendritic ntawm cov phab ntsa hauv plab hnyuv thiab ua ke, qhib thiab qhib cov proteins hauv cov hlwb kom txav mus rau hauv nuclei kom tso tawm ntau cov cytokines, txhim kho cov tsos mob ua xua los ntawm kev txhawb nqa kev tso tawm ntawm interleukin 12 (IL{ {1}}) thiab interferon gamma, thiab inhibit immunoglobulin IgE los ntawm stimulating plab hnyuv ib ntsuj av los tswj Th1 hom tiv thaiv kab mob, thiaj li hais tias cov allergic phenomenon ntawm Th1 thiab Th2 hom tiv thaiv kab mob ntau tshaj yog txhim kho; Lub caij no, cov khoom siv microbial npaj muaj cov kua qaub zoo thiab cov kua tsib ntsev ua rau lub cev thiab ua kom cov cell adhesion, tuaj yeem ua rau hauv cov hnyuv ntawm tib neeg lub cev rau ntau tshaj 60 hnub, thiab muaj kev cuam tshuam zoo rau cov kab mob xws li salmonella, escherichia coli, enterococcus. faecalis, salmonella typhimurium thiab lwm yam, yog li ua tiav cov txiaj ntsig ntawm kev ntxuav thiab tiv thaiv txoj hnyuv. Tsis tas li ntawd, lactobacillus casei, lactobacillus paracasei, lactobacillus plantarum, lactobacillus rhamnosus, lactobacillus reuteri, uas yog cov tswv cuab ntawm cov npe ntawm cov kab mob uas tuaj yeem siv rau zaub mov thiab suav nrog hauv Ministry of Health ntawm Tuam Tshoj, koom tes los txhawb kev ua haujlwm ntawm lactobacillus. ua si, thiab muaj cov nyhuv synergistic.