Lub ntsiab lus ntawm postbiotics
Lub koom haum International ntawm Probiotics thiab Probiotics (ISAPP) tau tshaj tawm cov lus pom zoo ntawm cov tshuaj metabiotics thaum lub Tsib Hlis 2021. Epibiotics, tseem hu ua "postbiotics," los yog metabolites, biogenic substances, los yog extracellular supernatants, xa mus rau cov khoom soluble secreted los ntawm cov kab mob nyob hauv metabolic los yog tso tawm tom qab cov kab mob tuag thiab kev sib cais, uas tuaj yeem muaj txiaj ntsig zoo rau tus tswv tsev. Cov ntsiab lus soluble no suav nrog luv-chain fatty acids (SCFAs), peptides, lipoteichoic acids, polysaccharide peptide complexes, endogenous thiab exogenous polysaccharides, kab mob sab nrauv membrane proteins, enzymes, vitamins, kua tsib acids, acetal phospholipids, isothiocyanates, thiab ntev chain fatty acids.
Cov kab mob ntawm postbiotics
Cov hom kab mob ntawm cov kab mob postbiotics feem ntau suav nrog cov npe ntawm cov kab mob uas tuaj yeem siv rau hauv cov zaub mov thiab lwm yam kab mob probiotics uas tau soj ntsuam kev nyab xeeb. Cov kab mob no feem ntau yog los ntawm tib neeg lub plab lossis cov khoom noj fermented, nrog rau cov kab mob, cov kab mob, thiab cov kab mob. (1) Lactobacillus, (2) Bifidobacterium, thiab (3) Enterococcus, nrog cov neeg sawv cev xws li Enterococcus faecalis thiab Enterococcus faecalis; (4) Streptococcus, (5) Bacillus, thiab (6) Clostridium yog dav siv hom Clostridium butyricum. Tsis tas li ntawd, kuj muaj Streptococcus mesenterium uas yog cov genus Streptococcus, Streptococcus lactis, Streptococcus npias, thiab Streptococcus pentose belongs rau genus Streptococcus, nrog rau cov kab mob bacteriocins tsim los ntawm Lactococcus kab mob xws li Nisin, Lactococcin, thiab Bacterocin. Raws li cov khoom siv roj ntsha, lawv muaj kev lag luam loj heev.
Kev noj qab haus huv mechanism ntawm postbiotics
Anti-inflammatory, antibacterial, thiab immunomodulatory teebmeem ntawm epigenetic ntsiab
Antioxidant muaj nuj nqi ntawm postbiotics
Cov nyhuv tiv thaiv ntawm postbiotics ntawm daim siab
Cov teebmeem ntawm kev txo cov ntshav siab, ntshav lipids, thiab poob phaus
Tiv thaiv thiab kho kev ua xua
Kev npaj ntawm postbiotics tuaj yeem tau txais los ntawm kev ua haujlwm ntawm tes thiab cov txheej txheem lysis, xws li kev kho cua sov, enzymatic hydrolysis, hluav taws xob ultraviolet, kev kub siab, hnyav extraction, thiab kev kho ultrasonic. Nws cov txheej txheem kev ua yeeb yam tuaj yeem ua tau ntxiv los ntawm kev siv cov txheej txheem rho tawm thiab purification xws li centrifugation, kem purification, thiab khov-drying.
Kev siv cov tshuaj epigenetic
Kev siv cov ntsiab lus epigenetic hauv kev lag luam khoom noj
Ntxiv nrog rau qhov muaj txiaj ntsig kev noj qab haus huv rau cov neeg siv khoom, cov ntsiab lus epigenetic tseem muaj peev xwm siv tau hauv kev khaws cia khoom noj khoom haus, ntim zaub mov, thiab tswj biofilm.
Kev siv cov tshuaj postbiotics hauv kev kho mob
Tam sim no, postbiotics khoom tau los ntawm fermenting sib txawv substrates nrog sib txawv probiotics muaj peev xwm siv tshuaj muaj nqis. postbioticscan yog ib lub tswv yim tshiab rau kev tiv thaiv thiab pab kho tej yam kab mob. Epibiotics tuaj yeem siv los txhim kho enteritis, txo cov cem quav, txhim kho plab hnyuv siab raum, thiab txo qis kev ua xua thiab kev ntxhov siab. Nws cov txheej txheem feem ntau suav nrog kev tswj hwm lub cev tiv thaiv kab mob, rov kho qhov sib npaug ntawm plab hnyuv microbiota, tiv thaiv plab hnyuv ua haujlwm, thiab cuam tshuam cov metabolism thiab cov teeb liab hloov. Nyob rau hauv lub neej yav tom ntej, kev nyab xeeb thiab kev noj qab haus huv cuam tshuam ntawm cov tshuaj epigenetic tseem yuav tsum tau soj ntsuam ntxiv los ntawm kev sim tshuaj.