Prebiotic Gut Flora Metabolism

Mar 26, 2022 Tso lus

Tom qab noj prebiotics, lawv mus ncaj nraim mus rau txoj hnyuv loj, qhov chaw uas lawv fermented los ntawm coliform kab mob rau kev siv lub zog, thiab tsim luv-chain fatty acids SCFA, feem ntau yog acetic acid, propionic acid thiab butyric acid, raws li zoo raws li lactic acid thiab roj. . [6]

(1) Acid ntau lawm

The organic acids generated by the intestinal flora metabolize food, on the one hand, can provide the energy needed by the human body, on the other hand, it can reduce the pH value of the intestinal tract and form an environment that is not conducive to the survival of pathogenic bacteria, thereby effectively inhibiting intestinal corruption and improving. The absorption rate of mineral elements, promote intestinal peristalsis and facilitate defecation. Generally, Lactobacillus only produces lactic acid, while Bifidobacterium mainly produces acetic acid and a small amount of lactic acid. After prebiotics are metabolized by intestinal flora, a large amount of organic acids will also be generated, which will lower the intestinal pH [7]. Among them, galacto-oligosaccharide and lactulose had the largest acid production, and inulin had the smallest acid production. The production of various organic acids after prebiotics are metabolized are: acetic acid LACT, GOS, SOS>FOS, IMO, XOS>Inulin; lactic acid GOS, SOS>XOS, IMO, LACT>FOS, Inulin; propionic acid LACT, Inulin , XOS, FOS>SOS, COS>IMO. [6]

(2) Gas ntau lawm

Ntxiv nrog rau bifidobacteria thiab lactobacilli hauv tib neeg txoj hnyuv, yuav luag tag nrho lwm cov nroj tsuag tuaj yeem tsim cov roj, ua rau tib neeg lub cev muaj kev sib txawv ntawm flatulence thiab farting. Tom qab prebiotics yog metabolized los ntawm cov hnyuv, qee cov pa roj xws li CO2, H2, thiab CH4 tuaj yeem tsim tau. Tos. Vim qhov sib txawv ntawm glycosidic daim ntawv cog lus thiab muaj pes tsawg leeg, ntau yam prebiotics yuav raug siv los ntawm ntau hom roj uas tsim cov kab mob, thiab cov roj tsim tawm yuav txawv. Rycroft et al. piv rau tag nrho cov roj tsim tawm ntawm cov prebiotics sib txawv los ntawm kev sim hauv vitro, thiab pom tias isomaltooligosaccharides thiab galactooligosaccharides yog cov prebiotics nrog tsawg kawg tag nrho cov roj tsim tawm, thaum inulin yog ib qho uas muaj cov roj ntau tshaj plaws (saib duab 3). Tsis tas li ntawd, Oku et al. [ua pov thawj kev soj ntsuam ntawm hydrogen ntau lawm ntawm peb prebiotics, oligofructose, oligofructose, thiab isomaltooligosaccharide. Tsis muaj teeb meem kev noj haus ntawm 10g / d lossis 20g / d, tag nrho cov oligomeric Fructose tsim cov roj hydrogen ntau tshaj plaws, thaum isomaltooligosaccharides tsim cov roj hydrogen tsawg kawg nkaus.


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